Adrenocorticotropin-independent macronodular adrenal hyperplasia
- VernacularTitle:非ACTH依赖性肾上腺皮质大结节增生症
- Author:
Yajing LI
- Publication Type:Journal Article
- Keywords:
Cushing syndrome;
Corticotropin;
Macron odular adrenal hyperplasia
- From:
Chinese Journal of Endocrinology and Metabolism
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To st ud y the characteristics of clinical manifestations and laboratory findings in pati ents with adrenocorticotropin-independent macronodular adrenal hyperplasia (AIM AH). Methods The clinical and laboratory findin gs of 4 patients with AIMAH were described and analyzed. Results All the 4 patients had clinical features and biochemical evide nce of Cushing′s syndrome. Plasma ACTH level was undetectable in all 4 patients . Serum cortisol secretion rhythm was abnormal. Low-and high-dose dexamethason e suppression tests failed to suppress cortisol secretion. CT examination showed bilateral macronodular adrenal enlargement. Conclusion AIMAH is recognized as a rare subtype of Cushing′s syndrome with uniqu e clinical and pathological findings.
