Association of membrane glycoprotein PC-1 gene K121 Q polymorphism with type 2 diabetes
- VernacularTitle:膜糖蛋白PC-1基因K121Q多态性与2型糖尿病相关性
- Author:
Mei XU
;
Ling XU
;
Kuanxiao TANG
;
Yuanguo SI
- Publication Type:Journal Article
- Keywords:
Membrane proteins;
Diabetes mellitus, n on-insulin-dependent;
Polymorphism, restriction fragment length
- From:
Chinese Journal of Endocrinology and Metabolism
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
K121Q polymorphism of membrane gl yc oprotein PC-1 gene was assayed by PCR-RFLP and distributions of Q, K alleles a nd KQ, KK genotypes were observed in 92 normal controls and 107 type 2 diabetic patients. The results suggest that Q allele is related to type 2 diabetes and ty pe 2 diabetes with obesity, hypertension and hyperlipidemia.
