Influence of DiKang capsule on expression of TGF? receptor Ⅱ on hepatic satellite cells in rat with liver fibrosis introduced by DMN
- VernacularTitle:迪康胶囊对二甲基亚硝胺诱导的肝纤维化大鼠星状细胞TGF?Ⅱ型受体表达的影响
- Author:
Wei WANG
;
Lihuang ZHANG
;
Hangping YAO
- Publication Type:Journal Article
- Keywords:
Hepatocirrbsis;
Hepatic satellite cell;
TGF?;
Receptor
- From:
Chinese Journal of Immunology
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the influence of DiKang capsule on expression of TGF? receptor Ⅱ on hepatic stellite cells(HSC)in rat with liver fibrosis introduced by DMN.Methods:TGF? receptor Ⅱ on HSC in rat with liver fibrosis introduced by DMN were measured by FCM.Results:In group of 10 ?g/kg DMN injected 3 weeks,expression of TGF? recptor Ⅱ on HSC in these rat fed with DiKang capsule 3 weeks were higher than that not feeding capsule.But in group of injecting 5 ?g/kg DMN continuous 6 weeks,expression of TGF? receptor Ⅱ on HSC does not changed with feeding or not feeding DiKang capsule.Conclusion:DiKang capsule may have a certainly role on expression of TGF? receptor Ⅱ on HSC in rat with liver fibrosis introduced by DMN.
