Relationship among expression of Cyclin D_1、p16、p27 and PCNA in glioma
- VernacularTitle:Cyclin D_1和p16、p27在脑胶质瘤中的表达及其与PCNA的相关性
- Author:
Zhihua WEN
;
Shiyu ZHAO
;
Zhiqiang LI
- Publication Type:Journal Article
- Keywords:
Glioma;
Cyclin D 1;
p16;
p27;
PCNA;
Correlation
- From:
Chinese Journal of Immunology
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the expression of Cyclin D 1?p16?p27 and PCNA in glioma with different pathological classification, and to explore the correlationship among Cyclin D 1?p16?p27 and PCNA.Methods:Cyclin D 1?p16?p27 and PCNA protein expressions in 12 normal brain tissues and 58 glioma cases were examined by immunohistochemical staining and hemiquantity analysis.Results:With the increasing of glioma malignancy, the expression level of Cyclin D 1 protein increased gradually (P
