Correlation of elastase and ?1-antitrypsin level in gingival crevicular fluid with periodontal inflammation
- VernacularTitle:龈沟液弹性蛋白酶及其抑制因子水平与牙周炎相关性的研究
- Author:
Ge SONG
;
Liu QI
;
Yan FUHUA
- Publication Type:Journal Article
- Keywords:
Periodontal diseases;
Diagnosis;
Gingival crevicular fluid;
Pancreatic elastase;
? 1-antitrypsin
- From:
Journal of Practical Stomatology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the correlation of elastase(EA) and ? 1-antitrypsin (? 1-AT) level in gingival crevicular fluid(GCF) of different periodontal status and their roles in periodontal inflammatary pathogenesis. Methods: 62 volunteers aged 45～51 years old were enroled.Their periodental status were examined and grouped into healthy periodontium (H),8 cases,marginal gingivitis (MG),12 cases,mild chronic periodontitis (MCP),20 cases and advanced chronic periodontitis (ACP),22 cases.EA in GCF were measured with a chromogenic low molecular weight substrate reaction and the ? 1-AT with ELISA. Results: Significantly positive correlation was found between GCF-EA activity and clinical periodontal parameters (P
