Clinical Study of Internal Radiotherapy with Hepatic Intra-ar te rial Iodine-131 Labeled Material for Hepatocellular Carcinoma
- VernacularTitle:~(131)I标记物介入治疗肝癌的临床研究进展
- Author:
Shaoping WU
;
Wusheng LU
- Publication Type:Journal Article
- Keywords:
Iodine-131 Hepatocellular carci noma Chemoembolization Internal radiation therapy
- From:
Chinese Journal of Bases and Clinics in General Surgery
2003;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the clinical val ue of internal radiation therapy with hepatic intra-arterial iodine-131 labele d material for the treatment of hepatocellular carcinoma (HCC). Methods This summarized paper was made on literatu re review. Results Iodine-131-lipiodol and several reported iodine-131-labeled antibodies to HCC associated antigens were concentrated in the foci of HCC with a high tumor-to-normal-tissue absorbed dose ratios. No s evere side effects occurred. It was used in various kinds of HCC patients, and m ostly showed a significant tumor response. Survival rate of HCC patients was rai sed in several clinical trials.Conclusion Internal radiotherapy with hepatic intr a-arterial iodine-131 labeled material may be considered as an effective metho d to treat HCC.