Comparison between C_2 and C_0 as a monitoring tool for domestic cyclosporin A microemulsion capsule
- VernacularTitle:国产环孢素A微乳胶囊血药浓度监测指标C_2与C_0的比较
- Author:
Fang QIAN
;
Hai WANG
;
Youhua ZHU
- Publication Type:Journal Article
- Keywords:
Cyclosporine;
Drug monitoring
- From:
Chinese Journal of Organ Transplantation
2003;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To testify the possibility that two-hour concentration (C_2) substituting for the target concentration (C_0) is used to be a monitoring tool for CsA. Method The whole blood concentrations of CsA having taken orally in 17 renal transplant patients were measured by FPIA. The data of concentration-time was processed by 3P87 pharmacokinetic program. Results The correlation between C_2 values and AUC_ 0-4 , or AUC_ 0-12 was both more excellent than C_0( P
