Clinical significance of the circulating chemokines in breast carcinoma patients
- VernacularTitle:乳腺癌患者外周血中趋化因子的检测及临床意义
- Author:
Gang LIU
;
Jie ZHANG
;
Jiong WU
- Publication Type:Journal Article
- Keywords:
chemokine;
angiogenesis;
breast neoplasm;
metastasis
- From:
China Oncology
1998;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Purpose: To investigate the plasma levels of chemokine IL-8, GM-CSF, RANTES and MCP-1 in patients with breast carcinoma and in healthy controls and to explore its clinical, pathologic and diagnostic significance. Methods: Enzyme linked immunosorbent assay ( ELISA) kits were used in 93 breast cancer patients and 20 health controls, and clinical significance was analysed. Results: The plasma levels of IL-8, RANTES and MCP-1 were significantly higher in the patients than in