Evaluation on the antiemetic effect of azasetron hydrochloride in patients with liver neoplasm after transcatheter arterial chemoembolization
- VernacularTitle:盐酸阿扎司琼对肝肿瘤患者TACE术后止吐疗效观察
- Author:
Chenggang WANG
;
Weili QIU
;
Zhaoxia QIAN
- Publication Type:Journal Article
- Keywords:
azasetron hydrochloride;
transcatheter arterial chemoembolization(TACE);
antiemetic effect;
liver neoplasms
- From:
China Oncology
1998;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Purpose: To evaluate the antiemetic effect of azasetron hydrochloride in patients with liver neoplasm after transcatheter arterial chemoembolization. Methods: 62 patients (33 with primary hepatocellular carcinoma and 29 with hepatic metastasis), who underwent transcatheter arterial chemoembolization( TACE) therapy 78 times in all, were allocated into the azasetron group( administration of azasetron hydrochloride) and the control group( administration of metoclopramide) randomly. The inhibitory effects on nausea and vomiting were observed in the two groups respectively. Results: The antiemetic CR ratio and the response rate( CR + PR) in the azasetron group was 81.0% and 99. 7%, respectively. These results were statistically higher than those in the control group( P
