Scoring Method for Early Prediction of Neonatal Chronic Lung Disease Using Modified Respiratory Parameters.
10.3346/jkms.2005.20.3.397
- Author:
Young Don KIM
1
;
Ellen Ai Rhan KIM
;
Ki Soo KIM
;
Soo Young PI
;
Weechang KANG
Author Information
1. Department of Pediatrics, University of Ulsan Hospital, Ulsan, Korea.
- Publication Type:Original Article ; Comparative Study
- Keywords:
Bronchopulmonary Dysplasia;
Infant, Premature;
Predictive Value of Tests;
ROC Curve;
Scoring Method;
Epidemiologic Research Design
- MeSH:
Analysis of Variance;
Birth Weight;
Chronic Disease;
Comparative Study;
Female;
Humans;
Infant, Newborn;
Lung Diseases/*diagnosis;
Male;
Predictive Value of Tests;
Prognosis;
Prospective Studies;
Respiratory Function Tests/*methods;
Retrospective Studies;
Sensitivity and Specificity;
Time Factors
- From:Journal of Korean Medical Science
2005;20(3):397-401
- CountryRepublic of Korea
- Language:English
-
Abstract:
In our previous study, we have demonstrated that peak inspiratory pressure over birth weight (PIP/kg) and mean airway pressure over birth weight (MAP/kg) were more significant risk factors for the development of neonatal chronic lung disease (CLD) than PIP and MAP. We aimed to develop a scoring method using the modified respiratory variables (SMUMRV) to predict CLD at early postnatal period. From 1997 to 1999, a retrospective review was performed for 197 infants <1,500 g for the development of the SMUMRV based on statistical analysis. From 2000 to 2001, calculated scores on day 4, 7 and 10 of life were obtained prospectively for 107 infants <1,500 g. Predictive values and the area under the receiver operator characteristic curve (AUC) were determined and compared with the result of the previous regression model. Gestational age, birth weight, 5 min Apgar score, PIP/kg at 12 hr of age, fractional inspired oxygen (FiO2), MAP/kg, modified oxygenation index and ventilatory mode were selected as parameters of SMUMRV. No significant differences of AUCs were found between the SMUMRV and the Yoder model. It is likely that our scoring method provides reliable values for predicting the development of CLD in very low birth weight infants.
