Islet autoantibodies and type 1 diabetes mellitus
- VernacularTitle:胰岛自身抗体与1型糖尿病
- Author:
Weiping DONG
;
Yuanfeng HU
;
Yufei WANG
;
Aifang ZHANG
;
Lijuan WANG
- Publication Type:Journal Article
- Keywords:
Islets of Langerhans;
Autoantibodies;
Diabetes mellitus, insulin-dependent
- From:
Chinese Journal of Endocrinology and Metabolism
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
The positive rate of autoantibodies was 29.7% in 1617 diabetic patients. The positive rate of monoautoantibody was lower than that of combined assay with 3 autoantibodies. Combined assay of multiple autoantibodies may enhance the positivity of early diagnosis of type 1 diabetes mellitus. Glutamic acid decarboxylase antibody (GADA) may be a better screening test for predicting insulin dependency, the prediction of GADA combined with protein tyrosine phosphatase antibody may approximate to 100%, whereas islet cell antibody assay may be needed in the adolescent patients.
