Association of polymorphism of CTLA-4 gene exon 1 with Graves′ disease in Chinese population
- VernacularTitle:中国人CTLA-4基因外显子1多态性与Graves病的相关性
- Author:
Qiaohong WANG
;
Yuezhong REN
- Publication Type:Journal Article
- Keywords:
Cytotoxic T lymphocyte associated antigen-4 gene;
Graves′ disease;
Polymorphism (Genetics)
- From:
Chinese Journal of Endocrinology and Metabolism
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
The polymorphism of cytotoxic T lymphocyte associated antigen-4 (CTLA-4) was investigated by PCR-RFLP in 28 healthy volunteers and 64 patients with Graves′ disease (GD). The result suggests that the frequency of G49 allele of CTLA-4 exon 1 in GD patients issignificantlyhigherthanthat in normal controls (P
