Electronic cloning and functional prediction of new apoptosis related gene 2ass-bnip3 of diabetic cardiomyopathy
- VernacularTitle:糖尿病性心肌病变凋亡相关新基因2ass-bnip3的电子克隆及其功能预测
- Author:
Fanglin ZHANG
;
Guo LI
;
Chao XIE
;
Di ZHANG
;
Wenzhong ZHOU
;
Guangwu XU
;
Gang CHEN
;
Weihua SUN
;
Min LUO
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus;
Myocardial disease;
Gene 2ass-bnip3
- From:
Chinese Journal of Endocrinology and Metabolism
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Using the technique of fluorescent-labled mRNA differential display, new apoptosis related gene 2ass-bnip3 of type 2 diabetic cardiomyopathy was found, the sequence of 1594 bp with coding 187 amino acids was obtained by the full-length clone, and its structural and functional predictions were performed. 2ass-bnip3 may play an important role in the development of diabetic cardiomyopathy via a regulatory pathway of calcium regulation and apoptosis.