Identification a HLA-A2-restricted CTL epitope of breast cancer differentiation antigen NY-BR-1
- VernacularTitle:抗原NY-BR-1的HLA-A2限制性CTL表位的初步鉴定
- Author:
Tingting ZHAO
;
Yuzhang WU
;
Zhihua LIN
- Publication Type:Journal Article
- Keywords:
Breast cancer;
NY-BR-1;
CTL epitope;
Prediction;
Identification
- From:
Chinese Journal of Immunology
2000;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To identify HLA-A2-restricted CTL epitope of breast cancer differentiation antigen NY-BR-1.Methods:The HLA-A2-restricted CTL epitope of breast cancer differentiation antigen NY-BR-1 is predicted by combination quantitative motif method and the molecular dynamics.The three epitope were assayed their affinity to HLA-A2.Results:The affinity to HLA-A2 of NY-BR-1_ 1043-1051 is a best.Conclusion:NY-BR-1_ 1043-1051 is a HLA-A2 restricted epitope.
