The effects of Qingluotongbi granule on the levels of cytokines in adjuvant induced arthritis rats
- VernacularTitle:清络通痹颗粒对佐剂性关节炎大鼠炎症细胞因子的影响
- Author:
Xueping ZHOU
;
Lingling ZHOU
;
Yaohong SONG
- Publication Type:Journal Article
- Keywords:
Qingluotongbi granule;
Adjuvant induced arthritis;
Interleukin-1;
Tumor necrosis factor alpha
- From:
Chinese Journal of Immunology
2000;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the effects of Qingluotongbi granule(QLT) on the changes of cytokines in adjuvant induced arthritis(AIA) model of rats.Methods:The AIA model of rats were induced by complete Freunds adjuvant. Various doses of QLT were given by gavage once daily for 21 days.Results:QLT〔7.2,14.4 g/(kg?d).ig〕markedly decreased the levels of IL-1 and TNF-? in AIA rats.Conclusion:QLT has modulating effects on the alternations of cytokines of AIA model.
