Endostatin expression in tumor tissues and serum levels of bladder cancer patients
- VernacularTitle:膀胱癌组织及血清中内皮抑素表达的意义
- Author:
Kaopeng GUAN
;
Shukun HOU
;
Xiaofeng WANG
- Publication Type:Journal Article
- Keywords:
Bladder neoplasms;
Carcinoma;
Endostatin
- From:
Chinese Journal of Urology
2001;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study endostatin expression in tumor tissues and serum levels of bladder cancer patients. Methods Expression of endostatin in 45 cases of bladder cancer and 12 subjects with normal bladder tissues was examined immunohistochemically.Serum levels of endostatin in 58 patients with bladder cancers and 43 healthy controls were analyzed by competitive enzyme immunoassay. Results Positive expression of endostatin was found in 61.5% patients with superficial bladder cancer,90.6% with invasive bladder cancer and 33.3% in normal bladder tissues.Serum level of endostatin was significantly higher in patients with bladder cancer than that in healthy controls (P
