The Clinical Applied Value of Embolic Substance of Microspheres of Fe_3O_4
- VernacularTitle:经动脉导管四氧化三铁微粒栓塞临床应用价值
- Author:
Xinbao CHENG
;
Shuguang YUAN
- Publication Type:Journal Article
- Keywords:
Fe 3O 4;
magnetic microsphere;
artery embolism;
interventional radiology
- From:
Journal of Practical Radiology
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical applied value of magnetic mitomycin microspheres and magnetic Fe 3O 4 in treating tumors and vascular diseases by embolism.Methods The embolic therapy in 106 cases useing microspheres or drugs of Fe 3O 4 under TV-guided through catheterization using Seldinger's technique were performed.Results In 94 malignant tumors and 12 benign vascular diseases.The most of tumors became small remarkably on CT,USG or BSA one month later after embolism.Pathology showed that necrosis of cancer tissue was 100 percent.Examination of blood biochemistry showed that the functions of liver and kidney had some changes,however these functions could recover to normal or better after therapy.AFP decreased significantly after embolism in most primary hepatic cancer.Changes in density of serum Fe before and after embolism showed that embolism of Fe 3O 4 microspheres could maintain serum Fe in normal condition.DSA showed that microspheres of Fe 3O 4 were moved from the near portion to the peripheral embolic arteries after embolism one month later and the clinical symptoes improved.Conclusion Fe 3O 4 is good embolic substance and can avoid some complications by embolism.
