The Expression and Significance of Multidrug Resistant Gene mdr1 in Hepatocellular Carcinoma
- VernacularTitle:多药耐药基因mdr1在肝细胞性肝癌中的表达及其意义
- Author:
Yi QUAN
;
Lnan YAN
- Publication Type:Journal Article
- Keywords:
Multidrug resistance gene mdr1 Hepatocellular carcinoma
- From:
Chinese Journal of Bases and Clinics in General Surgery
2003;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between mdr1 gene expression of hepatocellular carcinoma (HCC) and pathological characteristics,chemotherapy and prognosis. Methods The mdr1 gene expression of HCC in 56 patients with the methods of immunohistochemistry was studied. The results were analysed with the pathological data by statistic methods. Results The positive expression of mdr1 gene in cancer tissues and pericancerous tissues of HCC were 30/56(53.6%) and 19/56 (33.9%) respectively. The difference was statistically significant (? 2=4.39, P
