The expression of Th1/Th2 type cytokines in primary hepa-tic cancer tissue and its adjacent liver tissue
- VernacularTitle:原发性肝癌及癌旁组织中Th1/Th2类细胞因子表达模式
- Author:
Fabo QIU
;
Xihong JIANG
;
Liqun WU
;
Yun LU
;
Jinbo FENG
- Publication Type:Journal Article
- Keywords:
Liver neoplasms?Gene expression?Interferon type Ⅱ?Interleukin 2?Interleukin 4?Interleukin 10
- From:
Chinese Journal of Current Advances in General Surgery
1999;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the expression of Th1 versus Th2 type cytokines in primary hepatic cancer(PHC)and its adjacent liver tissues.Methods:The gene expression of Th1/Th2 cytokines was detected by RT-PCR using IFN-?and IL-2 as Th1 type cytokine genes,IL-4 and IL-10 as Th2 type cytokine genes.Results:Thl type cytokines were expressed in 7 and 9 cases,while Th0 type cytokines in 4 and 2 among 11 PHC and their adjacent liver tissues,respectively.Conclusion:Th1 type cytokines are expressed predominantly in primary hepatic cancer and its adjacent liver tissue.