Expressions of leptin receptor mRNA and neuropeptide Y mRNA in the hypothalamic arcuate nucleus of obese rat induced by high fat diet
- VernacularTitle:瘦素受体及神经肽Y mRNA在肥胖大鼠下丘脑弓状核的表达
- Author:
Shen QU
;
Dajin ZOU
- Publication Type:Journal Article
- Keywords:
Neuropeptide Y;
Receptors, leptin;
Arcuate nucleus
- From:
Chinese Journal of Endocrinology and Metabolism
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
The rat model of obesity was induced by high fat diet and in situ hybridization was performed with oligonucleotide probes.The results showed that expressions of leptin receptor mRNA and neuropeptide Y mRNA were significantly increased, suggesting that these increments might be related to leptin resistance.