Upregulatory effect of 17?-estradiol on estrogen receptor?expression in MG63 cells and human osteoblast-like cells
- VernacularTitle:17?-雌二醇对MG63细胞和正常人成骨细胞雌激素受体?表达的上调作用
- Author:
Eryuan LIAO
;
Xin SU
;
Xianghang LUO
- Publication Type:Journal Article
- Keywords:
Eslradiol;
Receptor, estrogen;
MC63 cells;
Human osteoblast-like cells
- From:
Chinese Journal of Endocrinology and Metabolism
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
The effect of 17?-estradiol ( 17?-E2 ) on expression of estrogen receptor ?( ER?) was observed in cultured MC63 cells and human osteoblast-like (HOB) cells. The results show that the expression of ER* is in a dose-dependent manner with 17p-E2 (0-1?10-6 mol/L) in MC63 cells and has an optimal 17?-E2 concentration (1?10-8 mol/L) in HOB cells resulting in maximum expression of ERp protein.
