Pancreatic ?-cell dysfunction and type 2 diabetes
- VernacularTitle:胰岛?细胞功能紊乱与2型糖尿病
- Author:
Yi SHI
;
Songhua WU
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus, non-insulin-dependent;
Insulin resistance;
Islet of Langerhans;
?-cellfunction
- From:
Chinese Journal of Endocrinology and Metabolism
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Both ?-cell dysfunction and insulin resistance contribute to the development of type 2 diabetes, and ?-cell function, especially early insulin secretion, is important in maintaining normal glucose tolerance. This review focuses on the ciritical role of ?-cell dysfunction in the pathogenesis of type 2 diabetes.