Correlation between neck lymph node metastasis and focal adhesion kinases expression in oral squamous cell carcinoma
- VernacularTitle:口腔鳞癌粘着斑激酶表达与颈淋巴结转移关系的研究
- Author:
Hongbing JIANG
;
Weidong TIAN
;
Shengwei LI
- Publication Type:Journal Article
- Keywords:
Mouth;
Squamous cell neoplasms;
Focal adhesion kinases;
Neck;
Lymph nodes;
Neoplasm metastasis
- From:
Journal of Practical Stomatology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the correlation between neck lymph node metastasis and focal adhesion kinases(FAK) expression in oral squamous cell carcinoma(OSCC). Methods: Immunohistochemistry LsAB technique was used to observe the expression of FAK in primary tumour and nodal metastasis of OSCC in 80 cases, correlation between the expression of FAK in OSCC and neck lymph node metastasis was analyzed statistically. Results: The results demonstrated that FAK was expressed in all 80 cases, the expression of FAK in the peripheral area of OSCC was stronger than that in central area (P
