Treatment of squamous cell carcinoma of maxillary sinus with a CVP chemotherapy through arterial injection
- VernacularTitle:CVP动脉灌注联合手术治疗晚期上颌窦鳞癌的疗效(附39例分析)
- Author:
Sanhu HE
;
Gang LI
;
Xiufent BAI
- Publication Type:Journal Article
- Keywords:
Maxillary sinus;
Neoplasms;
Drug therapy;
Lymphnode excision;
Treatment outcome
- From:
Journal of Practical Stomatology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To analyse the effects of CVP chemotherapy through arterial injection (CVPC) in the treatment of squamous cell carcinoma (SCC) of maxillary sinus.Methods:39 cases of primary squamous cell carcinoma of maxillary sinus at stage Ⅳ (M0) were treated with following regimen : carboplatin 300～350 mg/m 2 ia gtt on d1, etopside 100 mg ia gtt on d1～5, pingyangmycine 8 mg ia gtt on d1～5. The drugs were given through superficial temporal artery at the level of internal maxillary artery. Gave one cycle treatment before operation which was practised 4 weeks later.Results:Partly remission was found in all patients after chemotherapy. Pathological margin of original focus was negative after operation. 5 cases lost follow up. 4 cases were dead of distant metastasis (after 5,7,8 and 12 months respectively). 30 cases were alive without tumour. 17 cases were over 5 years, 6 over 3 , 4 over 1 and 3 less than one year.Conclusion: CVP arterial injection chemotherapy is effective in the treatment of SCC of maxillary sinus at late stage.
