Methylprednisolone's influence on the plasma plasminogen activator inhibitor-1 in lupus nephritis patients
- VernacularTitle:甲基强的松龙对狼疮性肾炎患者血浆中PAI-1的影响
- Author:
Dongmei ZHANG
;
Hua GU
;
Guangdong SUN
- Publication Type:Journal Article
- Keywords:
Methylprednisolone;
Lupus nephritis(LN);
Plasminogen activator inhibitor-1
- From:
Chinese Journal of Immunology
1985;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of methylprednisolone that decrease plasminogen activator inhibitor-1(PAI-1) in plasma through mediating the PA/plasmin system.Methods:Employed immunohistochemical technique-ELISA to determine PAI-1 level in plasma.Results:①PAI-1 in LN patients is significantly higher than that in the control group (P0.05).Conclusion:It is thus proved that methylprednisolone is capable of decreasing PAI-1 in plasma through mediating the PA/plasmin system and two shocks is the minimum for effective cure. [
