The preparation and the killer function on Hep-2 clone of bifunction antibody of anti-human laryngocarcinoma/anti-CD_3
- VernacularTitle:抗人喉癌/抗CD_3双功能抗体的制备及对Hep-2细胞株的杀伤作用
- Author:
Qingjie FENG
;
Shijun YAN
;
Liqun SUN
- Publication Type:Journal Article
- Keywords:
Laryngocarcinoma;
Anti-CD 3;
Bifunction antibody
- From:
Chinese Journal of Immunology
1985;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To prepare bifunction antibody of anti-human laryngocarcinoma/anti-CD 3 for the active immune therapy of laryngocarcinoma.Methods:To corss link monoclonal antibody of anti-human laryngocarcinoma and anti-CD 3 into bifunction antibody by chemical method,which can guide the killer function on carcinoma cells.Results:The killer rate of effector cells guided by bifunction antibody is higher than that of anti-CD 3 which can arise with the elevation of effect target ratio.Conclusion:Bifunction antibody of anti-human laryngocarcinoma/anti-CD 3 prepared by chemical cross linking method has the potential value for clinical application. [
