Effects of 830nm Semiconductor Laser Radiation on Damages of Chromosome and Sperm in Mice
- VernacularTitle:830nm半导体激光对小鼠染色体和精子的影响
- Author:
Guang LI
;
Shujuan LIU
;
Xuhong MIAO
- Publication Type:Journal Article
- Keywords:
Semiconductor laser;
Animals,laboratory;
Micronucleus;
Sperm
- From:
Journal of Environment and Health
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of different densities of830nm laser irradiation on genetic damages in mice cells.Methods 100Kunming mice were randomly divided into micronuleus groups and sperm group,as well as control group.Mice thymus glands and spleens were irradiated with an830nm semiconductor laser,30mW for5minutes or20minutes each day in vitro,and the micronuclei of polychromatic erythrocytes in sternum bone marrow and rate of abnormal sperm produced were determined.Results Laser irradiation induced deformed sperm(? 2 =111.747,P=0.000),while higher dose(20min per day)laser irradiation increased the micronuclei of polychromatic erythrocytes in sternum bone marrow.There was statistical significance in the difference between the rates of abnormal sperm and micronuclei in sternum bone marrow caused by irradiation on thymus and spleen(? 2 =27.395,P=0.000)and there was dosage effect.The spleen was the more sensitive.Conclusion Laser irradiation at830nm might have a genetic damages to mice cells.Attention should be paid to the potential hazardous effects induced by semiconductor laser irradiation.