Focal adhesion kinase and cancer
- VernacularTitle:黏着斑激酶与肿瘤
- Author:
Zhangyan HU
;
Wenqing LIU
;
Kangda LIU
- Publication Type:Journal Article
- Keywords:
FAK;
signal conduction;
cancer;
therapy
- From:
Basic & Clinical Medicine
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Focal adhesion kinase(FAK),the non-receptor tyrosine kinase,has been implicated in regulating a number of fundamental biological signal transudation pathways that control cell proliferation,survival,adhesion,motility.Many researches have reported that FAK highly expressed in many cancers and involved in the process of cancer development,such as initial,progress,metastasis,multi-drug resistance of cancer.FAK has been the hotpot in cancer research,and it will be a new target in cancer therapy.
