Effect of IL-?1 on EGF, EGFR and TGF?R_1 in fibroblasts of scars
- VernacularTitle:白介素1?对增生性瘢痕和瘢痕疙瘩中成纤维细胞的表皮生长因子、表皮生长因子受体及转移生长因子?R_1的影响
- Author:
Dongming CHEN
;
Qi WANG
;
Weihan BAO
- Publication Type:Journal Article
- Keywords:
Scar;
Fibroblasts;
Epidermal growth factor;
Epidermal growth factor receptor;
Transforming growth factor ?R 1
- From:
Chinese Journal of Medical Aesthetics and Cosmetology
2002;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05). After IL-1? was addied, densities of EGF, EGFR, TGF?R 1 were 224.00?31.59, 178.67?27.86 and 80.34?11.75 respectively in fibroblasts of normal skin; 128.75?18.31, 105.82?21.61 and 109.83?25.79 in fibroblasts of HS;113.01?24.71,93.34?30.71 and 118.75?19.27 in fibroblasts of keloid. Densities of EGF and EGFR in fibroblasts of normal skin was significantly higher than those in HS and keloid (P