The correlation of Schwann cell marker S100 protein and neural invasion in salivary adenoid cystic carcinoma
- VernacularTitle:雪旺细胞标志物S100蛋白在涎腺腺样囊性癌嗜神经侵袭中的意义
- Author:
Xiaolong LUO
;
Moyi SUN
;
Lianjia YANG
- Publication Type:Journal Article
- Keywords:
Salivary glands;
Adenoid cystic carcinoma;
Schwann cell;
Nneural invasion;
S100 protein
- From:
Journal of Practical Stomatology
1996;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
objective: To investigate the expression of Schwann cell marker S100 protein in salivary adenoid cystic carcinoma and try to find out the correlation of S100 expression and neural invasion of the tumor. Methods: Samples from 20 cases of adenoid cystic carcinoma(ACC) and 18 cases of mucoepidermoid carcinoma(MEC) were immunohistochemical stained with S100 antibody. Results: S100 was positive in all of the samples of the 20 cases of ACC and negative in all of MEC. Neural invasion was observed in 11 out of the 20 cases of ACC and in 2 of MEC. Conclusion: There may be Schwann cell differentiation in salivary adenoid cystic carcinoma, and it may be the histologic base of neural invasion of the tumor.
