Solitary Cavernous Sinus Neurosarcoidosis Mimicking Neurosyphilis.
10.3340/jkns.2014.55.1.61
- Author:
Dong Ha KIM
1
;
Won Ho CHO
;
Kyu Sup CHO
;
Seong Heon CHA
Author Information
1. Department of Neurosurgery, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea. mdcwh@naver.com
- Publication Type:Case Report
- Keywords:
Neurosarcoidosis;
Neurosyphilis;
Sarcoidosis;
Cavernous sinus
- MeSH:
Biopsy;
Brain;
Cavernous Sinus*;
Diagnosis, Differential;
Facial Pain;
Follow-Up Studies;
Granuloma;
Humans;
Magnetic Resonance Imaging;
Neurosyphilis*;
Prednisolone;
Sarcoidosis;
Syphilis
- From:Journal of Korean Neurosurgical Society
2014;55(1):61-63
- CountryRepublic of Korea
- Language:English
-
Abstract:
A differential diagnosis between neurosarcoidosis and neurosyphilis is particularly problematic in patients with a positive serologic result for syphilis. We report here a patient with a solitary cavernous sinus sarcoidosis who had a history of syphilis and showed rapidly progressing cavernous sinus syndrome. A transsphenoidal biopsy was performed and a histopathologic examination revealed a non-caseating granuloma with an asteroid body. His facial pain disappeared after steroid therapy. He received oral prednisolone for one year. A follow-up magnetic resonance imaging of the brain revealed resolution of the mass over the cavernous sinus. Particularly in patients with a history of syphilis, neurosyphilis should be included in a differential diagnosis of neurosarcoidosis.
