Urine nuclear matrix protein 22 and bladder tumor antigen test in the screening of bladder tumor recurrence
- VernacularTitle:联合核基质蛋白22与膀胱肿瘤抗原监测膀胱肿瘤复发的意义
- Author:
Kexin XU
;
Shukun HOU
;
Xiaofeng WANG
- Publication Type:Journal Article
- Keywords:
Bladder neoplasms;
Antigens,neoplasms;
Nuclear matrix protein 22
- From:
Chinese Journal of Urology
1994;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the quantitative determination of urine nuclear matrix protein 22 (NMP-22) and bladder tumor antigen (BTA) in the screening of bladder tumor recurrence. Methods 90 patients who had undergone TURBT were recruited in this study.Standard ELISA test was used to determine the quantity of NMP-22 in urine and urine BTA stat test was also performed.the findings were analyed with reference to the cystoscopic and pathological results. Results In comparison with the results of cystoscopy,urine NMP-22 test might denote 77% (32/43) recurrence of bladder cancer and this positive rate would increase to 93% (40/43) with the combined use of urine NMP-22 and BTA test. Conclusions Examination of NMP-22 in urine is a rapid and effective means of detecting the recurrence of bladder cancer.With the combined use of BTA test,urine NMP-22 determination might be a useful non-invasive method in screening the recurrence of bladder cancer,and the conventional invasive cystoscopy might be avoided.
