E-cadherin expression in prostate cancer and its correlation with PSA
- VernacularTitle:前列腺癌组织中E-cadherin表达及与PSA的关系
- Author:
Liqun ZHOU
;
Xiao HUANG
;
Yingqian LU
- Publication Type:Journal Article
- Keywords:
Prostatic neoplasms;
Carcinoma;
E-cadherin;
Prostate specific antigen
- From:
Chinese Journal of Urology
1994;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of E-cadherin in prostate cancer and its relationship with PSA. Methods E-cadherin expression of 56 prostate cancer samples were studied by immunohistochemical stain and its expression level was analyzed with respect to T-PSA, F-PSA and F/T ratio. Results 24 patients (43%) were normal and 32 patients (57%) were aberrant in E-cadherin expression. E-cadherin was related significantly to the grade and stage of cancer and the changes of F/T ratio.There were no significant relationship between E-cadherin expression and T-PSA or F-PSA. Conclusions E-cadherin expression may act as a marker to the malignant degree and the prognosis of the prostate cancer.
