The more perfection required, the less freedom we ha ve——difficulties and strategies in evaluating pancreatic islet ?-cell functi on for scientific research and clinical practice
- VernacularTitle:少些完美,多些自由——临床及科研工作中胰岛?细胞功能评估的困难与对策
- Author:
Guangwei LI
- Publication Type:Journal Article
- Keywords:
Islets of Langerhans;
?-cell function;
Evaluation;
Glucose tolerance test (Chin J Endocrinol Metab, 2003,19:5-7)
- From:
Chinese Journal of Endocrinology and Metabolism
1985;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Insulin secretion varies in a com pl icated manner including quantity released and timing, which is also regulated by both glucose load and insulin sensitivity. It makes the evaluation of ?-cell function difficult in scientific research as well as clinical practice. There is no any index that could reflect the function of insulin secretion perfectly so far. Therefore, it is necessary to have a clear understanding of the advantages and the disadvantages of the current available indices before to use them approp riately.