Detection of chromosomally abnormal fetuses by nuchal translucency
- VernacularTitle:超声探测颈部透明带检出胎儿染色体异常
- Author:
Hua MENG
;
Yuxin JIANG
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Fetus;
Chromosome abnormalities;
Nuchal translucency
- From:
Chinese Journal of Ultrasonography
1993;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the ultrasonographic detection of nuchal translucency or nuchal edema in identifying chromosomally abnormal fetuses.Methods Fetal nuchal translucency thickness was measured between 10～14 weeks of gestation,or nuchal fold thickness after 14 weeks,with serial follow-up ultrasound examinations.Results In a 2-year period,12 aneuploid fetuses had been identified,together with 5 fetuses of normal karyotype but fatal prognosis.Compared with the fetuses of increased nuchal translucency but normal karyotype and normal follow-up,they had a much thicker nuchal translucency in the first trimester (average 6.1 mm vs 3.6 mm),and in most cases the nuchal translucency evolved into nuchal edema in the second trimester,with other abnormalities detected by ultrasound.Conclusions Detection of increased nuchal translucency by ultrasound is effective in detecting chromosomally abnormal fetuses or fetuses with other abnomalities,and the changes of nuchal translucency observed by follow-up ultrasound may play an important role in differential diagnosis and predicting the prognosis.
