On the clinicopathology, ultrastructure and immunohistochemistry study of intracranial microcystic meningioma
- VernacularTitle:微囊型脑膜瘤临床病理、超微结构和免疫组化研究
- Author:
Yu LI
;
Ying YAN
;
Fulin SONG
- Publication Type:Journal Article
- Keywords:
microcystic meningioma;
pathology;
ultrastructure;
immunohistochemisry
- From:
China Oncology
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Purpose: To enhance one's ability to diagnose intracranial microcystic meningioma. Methods: Fifteen cases of intracranial microcystic meningioma have been studied either clinicopathologically, or ultrastructurally or immunohistochemically. Results: The results indicate that electron microscopy and immunohistochemically are very helpful for the diagnosis of the tumor. There was no predilection as to location, however the tumor was more common on the base of skull. Vacuole-like structure and/or vesicular dilatation could be seen in the cytoplasm and capillaries could be observed in between the spindle cells by light microscopy. Under electron microscopy, the processes separated from each other and formed into a cystic structure, and bundles of collagenous fiber could be found in it. In immunohistochemistry, the stains with vimentin and epithelium membrane antigen (EMA) were positive. Conclusions: Intracranial microcystic meningioma has some characteristics under the microscope, immunohistochemistry is helpful in its diagnosis, and election microscopy can confirm this diagnosis.
