Detection of interleukin-1? and tumor necrosis factor ? in serum and cerebrospinal fluid in patients with Alzheimer disease
- VernacularTitle:Alzheimer病病人血清与脑脊液白细胞介素-1及肿瘤坏死因子水平检测的研究
- Author:
Lin WANG
;
Jie HAN
;
Yu ZHANG
- Publication Type:Journal Article
- Keywords:
Alzheimer disease;
Interleukin 1;
Tumor necrosis factor
- From:
Chinese Journal of Neurology
1999;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the levels of interleukin 1? (IL 1?) and tumor necrosis factor ? (TNF ?) in both serum and CSF in patients with Alzheimer's disease Methods Eleven patients with Alzheimer's disease,13 patients with vascular dementia (VD) and 13 healthy controls were analyzed by using commercial ELISA kits Results The average serum level of IL 1? was found higher in AD patients(60 13?17 81 pg/ml) than in VD patients(38 51?14 39 pg/ml) and in healthy controls(33 98?16 31 pg/ml)( P
