Quantitative study of adiponectin mRNA expression in subcutaneous and omental adipose tissues of patients with type 2 diabetes
- VernacularTitle:2型糖尿病患者皮下、大网膜脂肪组织脂联素mRNA表达的定量研究
- Author:
Wei GU
;
Wenheng ZENG
;
Tohru FUNAHASHI
- Publication Type:Journal Article
- Keywords:
Adiponectin;
Diabetes mellitus, non insulin dependent;
Reverse transcriptase polymerase chain reaction;
Real time fluorescence quantitation
- From:
Chinese Journal of Endocrinology and Metabolism
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the adiponectin mRNA expression in subcutaneous and omental adipose tissues of type 2 diabetes and their relation with blood adiponectin, body weight index, waist hip ratio and insulin sensitivity. Methods The adiponectin mRNA expression level in adipose tissue of 22 cases with type 2 diabetes and 26 cases of non diabetes controls was assayed by real time fluorescence quantitative RT PCR. The level of plasma adiponectin was measured with ELISA kit. Results The adiponectin mRNA expression in omental adipose tissue was significantly decreased in patients with type 2 diabetes than that in non diabetes controls (P
