The changes of immunity and clinical significance in patients with cervical cancer before and after radiotherapy
- VernacularTitle:宫颈癌放疗前后免疫功能改变及其临床意义
- Author:
Hong PU
;
Chengzhang HE
;
Feng WANG
- Publication Type:Journal Article
- Keywords:
Cervical cancer Radiotherapy T lymphocyte subset Natural kill cells Flow cytometry
- From:
Chinese Journal of Immunology
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the influence of radiotherapy on immunity of patients with cervical cancer Methods:22 cancer patients and 20 patients with gynecological benign tumor were immunothenotype by flow cytometry Results:There was no obvious difference in immunity between cancer patients and control group After radiopherapy, ratio CD3 +/CD4 + decreased and the number of CD8 + and NK cells increased in cancer patients Conclusion:No immunodepression appeared in patients with cervical cancer before therapy Radiotherapy decreased immunity, which indicates adjuvant immunotherapy should be given during radiotherapy
