The anti inflammatory and diuretic effects and acute toxicity of aqueous extract of psychotria morindoides hutch on rat and mice
- Author:
Dao Van Phan
- Publication Type:Journal Article
- Keywords:
psychotria morindoides hutch, diuretic, anti inflammatory
- MeSH:
drugs;
Anti-Inflammatory Agents;
Diuretics;
toxicity;
Psychotria;
Animal Experimentation;
Mice;
Rats
- From:Journal of Medical Research
2003;25(5):3-7
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
The 1:1 aqueous extract of Radix Psychotria morindoides Hutch – Rubiacease with an oral dose of 10g/kg body weight of rat: Has no acute and anti-inflammatory effect on carrageenin – indecued edema in hind paw, but it reduces the asbestos induced granuloma as a subchronic inflammation medel. Increases the excretion of urine up to 83% at the sixth hour after drug ingestion. DL50 of the aqueous extract could not be determined because of its very low toxicity.
