Study on mRNA expression of P2y receptors of sciatic nerve in rate
- VernacularTitle:大鼠坐骨神经ATP受体mRNA表达的实验研究
- Author:
Shuanke WANG
;
Zhiying ZHANG
;
Guangxiang HONG
- Publication Type:Journal Article
- Keywords:
P 2y receptor;
mRNA expression;
Sciatic nerve
- From:
Chinese Journal of Microsurgery
2000;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To demonstrate the presentation of the extracellula ATP receptors in peripheral nerve in rats Methods Reverse transcriptase polymerase chain reaction was performed in sciatic nerve of rat Results There were three P2y receptor mRNA expressions in the in the sciatic nerve of the rat,they were P2y2 and P2y4 as well as P2y6 Conclusions Extracellular ATP,as a neurotransmitter,activates the P2y purinoceptors located on the axon regeneration after peripheral nerve injury and decided the direction of the regeneration axon The P2y receptors are related to the regeneration of the peripheral nerve
