Significance of colorectal carcinoma - associated antigen LEA in diagnosis of patients with colorectal carcinoma
- VernacularTitle:大肠癌相关抗原LEA在大肠癌诊断中的意义
- Author:
Hui FENG
;
Jindan SONG
- Publication Type:Journal Article
- Keywords:
Colorectal cancer Colorectal carcinoma-associated antigen Large external antigen (LEA) Diagnosis
- From:
Chinese Journal of Immunology
2000;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To probe into the expression and the clinic significance of LEA on colorectal carcinoma. Methods:The expression of LEA and CEA in 140 colorectal cancer specimens and 100 colorectal non-cancerous specimens had been detectd by immunohistcchemistry S-P method.Results:The expression of LEA was relative to tumor differentiation degree and exhibits higher selectivity in high differentiation ade-nocarcinoma ( P 0.05) . The positive rate of LEA in adenoma was much higher than surrounding non-cancerous mucosa and normal mucosa. In normal mucosa the positive rate of LEA was obviously lower than that of CEA ( P
