Effects of Grifola frondosa extracts on mouse immunity
- VernacularTitle:灰树花提取成分对小鼠免疫功能影响的实验研究
- Author:
Bin WEN
;
Changlong L■
;
Yaming CAO
- Publication Type:Journal Article
- Keywords:
Grifola frondosa extracts Nature killer cells Macrophages TNF? IL-1
- From:
Chinese Journal of Immunology
2000;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective :To investigate the effects of ethanol precipitate(ET-Pre) and RNA of Grifola frondosa on non-specific immunity in mouse.Methods:The common biological methods were used to examine the levels of cytokines and immunocyte activity. Results: The killing activity of the NK cells, the phagocytosis function of macrophages and the levels of TNF?/IL-1 in the animals treated with ET-Pre and RNA respectively were significantly higher than those in the control.The RNA was stronger than ET-Pre in increasing killing activity of NK cells and phagocytosis function of macrophages. Conclusion:Both ET-Pre and RNA extracts of Grifola frondosa may promote immunoactivity nonspecifi-cally and inhibit tumor cells indirectly.
