Determination and clinical significance analysis of ANF、PRA、AT-Ⅱ and ALD in the heart failure patients
- VernacularTitle:心血管疾患血浆ANF和PRA、AT-Ⅱ、ALD变化的临床意义
- Author:
Junhui LIANG
;
Fengqin CHEN
;
Fang ZHOU
- Publication Type:Journal Article
- Keywords:
Heart failure patients CHF Atrlal Natruluretle polypeptide Renin-Angiotensin-ll-Aldosterone
- From:
Chinese Journal of Immunology
2000;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of ANF, PRA, AT-? and ALD on the occurrence of Heart failure patients and Congestive heart failure(CHF) .Methods:The plasma were measured by radioimmunoassay(RIA) in 163 patients(112 on heart failure patients,51 congestive heart failure)before and after taking Angiotensiin converting enzyme. The results were as foron: ll. Results:The concentrations of ANF, PRA,AT-? and ALD in acute myocardid infarction, Rheumatic valvuar disease, cor pulmonale and Hypertension patients were higher significantly than the contorl group(heart failure)( P 0.05) .After taking ACE inhibitor,AT an extent, the values were decreased-ANF 32.5%, AT-? 25.3 % and ALD 27.1 % , A positive correlation was shown between ANF system and RSSA system. Conclusion: The results suggested that monitoring of ANF,PRA,AT-? and AID with RIA technique showed a beneficial to heart's disease and heart's dysfunction.
