The study on hematological changes of nontraumatic osteonecrosis of the femoral head
- VernacularTitle:非创伤性股骨头坏死患者的血液学改变
- Author:
Zhaomin ZHENG
;
Xuhua LU
;
Tianhua DONG
- Publication Type:Journal Article
- Keywords:
Femur head,necrosis;
Enzyme-linked immunosorbent assay;
Plasminogen activators in-hibitor;
Protein C;
Discriminant an alysis
- From:
Chinese Journal of Orthopaedics
1999;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the hematological changes o f nontraumatic osteonecrosis of the femoral head,select the sensitive molecular symbols for early diagnosis and distinguish the high risk peopl e.Methods The studied subjects were divided in to three groups:1)NONFH early stage group(n=30);2)NONFH late stage group(n=30);3)the normal controlled group(n=30).Blood samples from cubital veins were collected.GMP -140,PC,D -Dime r were examined using ELISA.PAI was e xamined with chromogenic assay.Results1)The platelet GMP -140levels of early or late stage groups NONFH were signi ficantly higher than that of the normal contro lled group;the plasma PC levels of both groups were lower than that of the normal controlled group significan tly(P