Study on the change of interleukin-4 and interleukin-12 following active immunization of women with unexplained habitual abortion
- VernacularTitle:原因不明习惯性流产患者主动免疫前后IL-4、IL-12变化的研究
- Author:
Lihua QIU
;
Qide LIN
;
Zhongyi SEEN
- Publication Type:Journal Article
- Keywords:
Habitual abortion Interfeukin-4 Interleukin-12 Immunotherapy
- From:
Chinese Journal of Immunology
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the changes of interleukin(IL)-4 and IL-12 following active immunotherapy of women with unexplained habitual abortion(UHA) .Metbods:The expression of IL-4 and IL-12 mRNA was measured by semi-quantitative reverse transcription-polymerase chain reaction (RT-PCR) in peripheral blood mononuclear cells(PMBC) . The samples were taken from 30 non-pregnant(NNP) women and 30 UHA women before and three weeks after active immunotherapy.Results: (1)IL-4 mRNA expression was lower significantly ( P
