Expression of cytokine in CD69 cell and CD69 on lymphocyte from patients with systemic lupus erythematosus
- VernacularTitle:系统性红斑狼疮患者淋巴细胞CD69表达及细胞因子水平研究
- Author:
Furong LI
;
Zhizhong YE
;
Yong DAI
- Publication Type:Journal Article
- Keywords:
Systemic lupus erythematosus(SLE) CD69+ IL-2 TNF? Flow cytometric analysis
- From:
Chinese Journal of Immunology
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the expression of CD69+ on lymphocyte and cytokine in active lymphocyte (CD69+) from patients with systemic lupus erythematosus( SUE) . So try to understand the lymphocyte activation, expression of cytokine in active lymphocyte and the pathogenesis of SLE.Methods: Expression of CD69+ on lymphocyte and intracellular cytokine(IL-2,TNF?) in active lymphoycte(CD69+) were investigated in 26 SLE and 15 healthy volunteers by using flow cytometric analysis and immunofluorescence staining method. Results:Expression of CD69+ on lymphocytes from active and inactive SLE patients were significantly higher than that of healthy controls( P
