Telomerase activity in transitional cell carcinoma after intravesical instillations of Serratia Marcescens
- VernacularTitle:粘质沙雷菌苗膀胱灌注前后肿瘤组织端粒酶活性的变化
- Author:
Xiaowen HE
;
Jun LI
;
Xiaoqing JIN
- Publication Type:Journal Article
- Keywords:
Bladder neoplasms;
Carcinoma;
Telomerase;
Serratia Marcescens
- From:
Chinese Journal of Urology
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study changes of telomerase activity in transitional cell carcinoma after intravesical instillation of Serratia Marcescens . Methods TRAP-PCR and TRAP-sliver staining were used to detect telomerase activity in 20 patients with TCC after intravesical instillation of Serratia Marcescens . Results Positive rate of telomerase activity detection in TCC patients after intravesical instillation of Serratia Marcescens was 50%(10/20),significantly lowed than before the intravesical instillation (90%,18/20), P