Clinical significance of E-Cadherin expression in breast carcinoma
- VernacularTitle:E-Cadherin基因在乳腺癌中的表达及临床意义
- Author:
Xiangqian GONG
;
Nanhai SHOU
;
Yongshen ZHANG
- Publication Type:Journal Article
- Keywords:
Mamary neoplasms;
Gene,E-Cadherin;
Lymphatic matastasis
- From:
Chinese Journal of Current Advances in General Surgery
1999;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinical significance of E-Cadherin (E-CD) expression in breast carcinoma.Methods:The expression of E-CD gene in human breast carcinomas was studied by immunohistochemistry(SABC) in 92 patients and the relationship between the expression and the clinical pathologic parameters was observed.Results:The positive rate of E-CD expression was 48.9%(45/92).The group with negative E-CD expression has higher incidence of distant metastasis (34%,16/47)than the positive one (15.6%,7/45)(P
