Effects of aqueous joint extracts during CIA development on the HUVEC proliferation and expression of VEGF
- VernacularTitle:关节炎小鼠关节组织提取物对内皮细胞增殖影响及mVEGF的关系
- Author:
Jing LU
;
Ping HOU
;
Ning ZHANG
- Publication Type:Journal Article
- Keywords:
Arthritic Extract Endothelial cell Growth factor
- From:
Chinese Journal of Immunology
1985;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effects of extracts of aqueous joint during CIA development on the HUVEC proliferation in vitro and expression of VEGF Methods: 3H TaR incorporation was used to estimate the HUVEC proliferation by extracts of aqueous joint and VEGF, and was used cultured in an absolutely serum free medium Results:Extracts of aqueqous joint during CIA development stimulated proliferation of HUVEC and this proliferation was inhibited by the anti VEGF neutralizing antibody Conclusion:The expression of VEGF in the extracts of the aqueous joint during an early stage of CIA development increased and expressed biologically active
